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CANNABINOIDS 101

HHM has updated their testing equipment and now include in greater detail the cannabinoids present in your products, beyond just THC and CBD content. This new method being used is called High Performance Liquid Chromatography. (To read more about HPLC click HERE.) 

But what do all these new compounds mean and why should we care about them? 

Cannabis contains at least 85 types of cannabinoids, which are the chemical compounds secreted by the cannabis flower.  These compounds can provide relief to a variety of symptoms, including, but not limited to pain, nausea and inflammation. 

CBD-V (Cannabidivarin)

CBD-V is a non-psychoative cannabinoid that will not cause the euphoric feeling of being “high”. It is found more prevalently in indica strains, specifically landrace indica plants, and ones that are generally lower in THC. 

Like CBD, CBD-V can significantly reduce the frequency and severity of seizures. It can also reduce or even eliminate nausea associated with several conditions, and helps to reduce inflammation throughout the body. CBD-V has also shown benefits in the treatment of pain and mood disorders. 

This is an excerpt from an article on the website leafly.ca. To read more about CBD-V click HERE.

CBD-A (Cannabidiolic Acid)

CBD-A is abundant in the live plants of CBD varieties. It converts to the better known cannabinoid CBD (cannabidiol) over time and when exposed to heat. While most cannabinoids bind directly with either the CB1 (brain) or CBD2 (body) receptors, CBD-A does not work this way. Instead, CBD-A interacts with the endocannabinoid system by inhibiting the cyclooxygenase-2 (COX-2) enzyme. COX-2 enzymes are associated with inflammation after injury or infection, so by blocking C)X-s enzymes, CBD-A can relieve inflammation and associated pain. 

This is an excerpt from an article on the website leafly.ca. To read more about CBD-A click HERE.

CBG (Cannabigerol)

CBG is usually considered a minor cannabinoid (levels are usually less that 1%). CBD helps to produce and regulate endocannabinoids, while CBG works on the receptors. Another way to differentiate the two – CBG typically energizes, while CBD has a more calming effect. The two balance each other out when taken together. 

CBG has been found to act on very specific physiological systems and problems, and results for medicinal use are promising. 

This is an excerpt from an article on the website Leafly.ca. To read more about CBG click HERE

CBD (Cannabidiol)

Unlike THC, CBD does not make a person feel “stoned” or intoxicated. That’s because the two cannabinoids act in different ways on different receptors in the brain and body. CBD can actually lesson or neutralize the psychotic effects of THC, depending on how much of each compound is consumed. Many people want the health benefits of cannabis without the high, or less of a high. The fact that CBD is therapeutically potent as well as non-intoxicating makes it an appealing treatment option for those cautious about trying cannabis. 

Research and mounting anecdotal accounts from patients and physicians highlight CBD’s potential as a treatment for a wide range of ailments including, but not limited to:

Autoimmune diseases, neurological conditions, metabolic syndromes, gut disorders, cardiovascular dysfunction and skin diseases. 

This is an excerpt from an article on the website projectcbd.org. To read more about CBD click HERE

THC-V (Tetrahydrocannabivarin) 

THC-V is a compound in cannabis that offers a unique array of effects and medical benefits that sets it apart from other cannabinoids like THC and CBD. As its name suggets, THC-V is similar to THC in molecular structure and psychoactive properties, but it provides a variety of very different effects. THC-V may dull the appetite and research shows promise in it’s ability to regulate blood sugar levels and reduce insulin resistance. It also appears to curb anxiety attacks in PTSD patients without suppressing emotion, as well as improve tremors, motor control, and brain lesions associated with Alzheimers disease. More research is needed on all subjects. 

This is an excerpt from an article on the website Leafly.ca. To read more about THC-V click HERE.

CBN (Cannabinol)

CBN is a non-intoxicating compound that is best known as the cannabinoid created when THC ages. It is usually found in high amounts in older cannabis. While this may be a turn-off for some, others seek out older flower to enjoy the effects of CBN.

A few potential medical benefits currently being researched include: a potential antibacterial agent, neuroprotectant, appetite stimulation, glaucoma, anti-inflammation. 

Please note, current research on CBN is limited with very few studies demonstrating its effects in the human body. 

This is an excerpt from an article on the website Leafly.ca. To read more about CBN click HERE

THC-9 (Tetrahydrocannabinol, or Delta-9 THC)

Delta-9 THC is a major cannabinoid found in abundance in cannabis. THC-9 is the most well-known compound in the plant and is capable of inducing a variety of sensory and psychological effects, including euphoria, increased sensory awareness and some therapeutic benefits. Historically, cannabis has been cultivated for its euphoric and therapeutic effects which are largely attributed to this Delta-9 THC molecule. 

This is an excerpt from an article on the website weedmaps.com. To read more about THC-9 click HERE

CBC (Cannabichromene)

CBC is considered one of the “big six” cannabinoids prominent in medical research. CBC is non-intoxicating, so it doesn’t produce a euphoric high like THC. The reason it is non-intoxicating is because it doesn’t bind well to CB1 receptors in the brain. But CBC does bind with other receptors in the body, such as the vanilloid receptor 1 (TRPV1) and transient receptor potential ankrin 1 (TRPA1), both of which are linked to pain perception. 

While CBC definitely has singular benefits, researchers also think it seems to synergistically work with other cannabinoids, a term known as the entourage effect. 

Some medical conditions that may be alleviated by CBC are: cancer, pain and inflammation, acne, depression. 

This is an excerpt from an article on the website Leafly.ca. To read more about CBC click HERE

THC-A (Tetrahydrocannabinolic Acid)

THC-A is a non-intoxicating cannabinoid found in raw and live cannabis. As the plant dries, THC-A slowly converts to THC. Heat expedites this conversion in a process known as decarboxylation, which is what happens when you smoke or vaporize flower. With tested cannabis the most abundant cannabinoid is either THC, or THC-A. While THC-A is the more accurate label for flower that hasn’t been decarboxylated, the two terms essentially mean the same thing, assuming one intends on smoking, vaporizing or heating the product in some way. But THC-A has its own unique properties if it isn’t converted to THC, such as anti-inflammatory, anti-emetic, anti-proliferative and neuroprotective properties. More research is needed in all categories. 

Every high THC strain that has not yet been decarboxylated contains THC-A, particularly live or freshly harvested plants. For this reason, raw cannabis parts are popularly juiced for the THC-A benefits. 

This is an excerpt from an article on the website Leafly.ca. To read more about THC-A click HERE

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